Detalhe da pesquisa
1.
Drug delivery systems for RNA therapeutics.
Nat Rev Genet
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Artigo
em Inglês
| MEDLINE | ID: mdl-34983972
2.
Cationic cholesterol-dependent LNP delivery to lung stem cells, the liver, and heart.
Proc Natl Acad Sci U S A
; 121(11): e2307801120, 2024 Mar 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38437539
3.
The Transcriptional Response to Lung-Targeting Lipid Nanoparticles in Vivo.
Nano Lett
; 23(3): 993-1002, 2023 02 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-36701517
4.
Multivalent Targeting of the Asialoglycoprotein Receptor by Virus-Like Particles.
Small
; 19(52): e2304263, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37649182
5.
The Extent to Which Lipid Nanoparticles Require Apolipoprotein E and Low-Density Lipoprotein Receptor for Delivery Changes with Ionizable Lipid Structure.
Nano Lett
; 22(24): 10025-10033, 2022 12 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-36521071
6.
Universal Barcoding Predicts In Vivo ApoE-Independent Lipid Nanoparticle Delivery.
Nano Lett
; 22(12): 4822-4830, 2022 06 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-35671473
7.
High-throughput in vivo screen of functional mRNA delivery identifies nanoparticles for endothelial cell gene editing.
Proc Natl Acad Sci U S A
; 115(42): E9944-E9952, 2018 10 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-30275336
8.
A Direct Comparison of in Vitro and in Vivo Nucleic Acid Delivery Mediated by Hundreds of Nanoparticles Reveals a Weak Correlation.
Nano Lett
; 18(3): 2148-2157, 2018 03 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-29489381
9.
Substituting Poly(ethylene glycol) Lipids with Poly(2-ethyl-2-oxazoline) Lipids Improves Lipid Nanoparticle Repeat Dosing.
Adv Healthc Mater
; : e2304033, 2024 Feb 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38318754
10.
Substituting racemic ionizable lipids with stereopure ionizable lipids can increase mRNA delivery.
J Control Release
; 353: 270-277, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36423872
11.
Small interfering RNA-mediated allele-selective silencing of von Willebrand factor in vitro and in vivo.
Blood Adv
; 7(20): 6108-6119, 2023 Oct 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-37467023
12.
Nanoparticle stereochemistry-dependent endocytic processing improves in vivo mRNA delivery.
Nat Chem
; 15(4): 508-515, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36864143
13.
High-throughput screens identify a lipid nanoparticle that preferentially delivers mRNA to human tumors in vivo.
J Control Release
; 357: 394-403, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37028451
14.
Species-dependent in vivo mRNA delivery and cellular responses to nanoparticles.
Nat Nanotechnol
; 17(3): 310-318, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35132167
15.
Nanoparticle single-cell multiomic readouts reveal that cell heterogeneity influences lipid nanoparticle-mediated messenger RNA delivery.
Nat Nanotechnol
; 17(8): 871-879, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35768613
16.
Augmented lipid-nanoparticle-mediated in vivo genome editing in the lungs and spleen by disrupting Cas9 activity in the liver.
Nat Biomed Eng
; 6(2): 157-167, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35190679
17.
Therapeutic RNA Delivery for COVID and Other Diseases.
Adv Healthc Mater
; 10(15): e2002022, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33661555
18.
Treating Cystic Fibrosis with mRNA and CRISPR.
Hum Gene Ther
; 31(17-18): 940-955, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32799680
19.
Nanoparticles containing constrained phospholipids deliver mRNA to liver immune cells in vivo without targeting ligands.
Bioeng Transl Med
; 5(3): e10161, 2020 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-33758781
20.
Increased PIP3 activity blocks nanoparticle mRNA delivery.
Sci Adv
; 6(30): eaba5672, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32743074